Figure 5.

Activin overexpression inhibits the production of IgEs after OVA treatment. WT and K14-Act mice treated with OVA or vehicle were sacrificed, and serum was collected. Total IgE (A), OVA-specific IgE (B), and total IgG2a (C) ELISA were performed as described in Section “Materials and Methods.” The data are presented as a scatter plot and mean values are shown (n = 8–12). Statistically significant differences were calculated with the Mann–Whitney U-test (p < 0.05* and p < 0.01**).