Skip to main content
. 2013 Jul 19;154(9):3031–3042. doi: 10.1210/en.2012-2195

Figure 4.

Figure 4.

Loss of the mammary gland CaSR reduces biochemical indices of bone formation but does not increase biochemical markers of bone resorption during lactation. A, Results for serum CTX in control and CaSR-cKO mice on day 12 of lactation. There was no significant increase in rates of bone resorption in CaSR-cKO mice. Bars represent the mean ± SEM for 6 mice of each genotype. B, Serum osteocalcin levels in control and CaSR-cKO mice on day 12 of lactation. There was a significant decrease in circulating osteocalcin levels in cKO as compared with control mice. Bars represent the mean ± SEM for 6 mice of each genotype. C, Serum P1NP levels in control and CaSR-cKO mice on day 12 of lactation. There was a significant decrease in circulating P1NP levels in cKO as compared with control mice. Bars represent the mean ± SEM for 4 control mice and 6 CaSR-cKO mice.