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. 2013 Aug;94(Pt 8):1691–1700. doi: 10.1099/vir.0.049254-0

Fig. 1.

Fig. 1.

RAGE fails to block F protein-mediated RSV infection. (a) Expression of RAGE on parental HEK and HEK-RAGE cells. Ab, anti-RAGE antibody. (b–d) RSV infection of HEK and HEK-RAGE cells assessed by measuring membrane expression of the F protein by flow cytometry after 16 h. (b) HEK-RAGE cells without viral infection (grey shading), and HEK-RAGE (grey line) or HEK (black line) cells infected with live virus at the indicated m.o.i. (c) HEK-RAGE cells without viral infection (grey shading), and HEK-RAGE (grey line) or HEK (black line) cells infected with UV-irradiated (UV irr) virus at an m.o.i. of 0.5. (d) Parental HEK cells without virus (grey shading), and HEK cells infected with live RSV virus (black line) or with live virus and 300 nM soluble RAGE-Fc (sRAGE) (dotted line).