Table 4. Associations of HEY1, HES1 and SOX9 expression with overall survival, stratified by AJCC stage.
| Dependent variable | AJCC Stage | Deaths | HR | 95% confidence interval of HR | P-value |
|---|---|---|---|---|---|
|
Tumour HEY1 | |||||
| II | 115 | 1.05 | 0.8–1.4 | 0.728 | |
| |
III |
91 |
1.34 |
1.1–1.7 |
0.007 |
|
Tumour HES1 | |||||
| II | 106 | 0.98 | 0.8–1.2 | 0.816 | |
| |
III |
89 |
1.23 |
1.0–1.5 |
0.037 |
|
Tumour SOX9 | |||||
| II | 107 | 1.02 | 0.8–1.3 | 0.829 | |
| III | 90 | 1.29 | 1.0–1.6 | 0.022 | |
Abbreviations: 5-FU=5-fluorouracil chemotherapy; AJCC=American Joint Committee on Cancer; HR=hazard ratio.
Cox regression survival analyses were age and sex adjusted.