Table 5.
Diagnostic validity for different test combinations using cut-offs derived from ROC analysis.
| Tests | Cut-off used | Sensitivity (CI 95%) |
Specificity (CI 95%) |
LR+ (CI 95%) |
LR− (CI 95%) |
|---|---|---|---|---|---|
| NPC recovery | NPC recovery ≥ 8.25 cm | 0.85 (0.69–1) |
0.82 (0.61–1) |
4.79 (1.69–14) |
0.19 (0.08–0.48) |
| NPC recovery + BAF | NPC recovery ≥ 8.25 cm BAF ≤ 8.25 cpm |
0.77 (0.59–0.95) |
1 (0.97–1) |
NA | 0.23 (0.13–0.49) |
| NPC recovery + BAF + NPC break | NPC recovery ≥ 8.25 cm BAF ≤ 8.25 cpm NPC break ≥ 5.35 cm |
0.73 (0.54–0.92) |
1 (0.97–1) |
NA | 0.27 (0.15–0.53) |
| NPC recovery + BAF +NPC break + MAF | NPC recovery ≥ 8.25 cm BAF ≤ 8.25 cpm NPC break ≥ 5.35 cm MAF ≤ 8.25 cpm |
0.58 (0.37–0.79) |
1 (0.97–1) |
NA | 0.42 (0.28–0.68) |
| NPC recovery + BAF + NPC break + MAF + VF | NPC recovery ≥ 8.25 cm BAF ≤ 8.25 cpm NPC break ≥ 5.35 cm MAF ≤ 8.25 cpm VF ≤ 14.75 cpm |
0.42 (0.21–0.63) |
1 (0.97–1) |
NA | 0.58 (0.42–0.82) |
| NPC recovery + BAF +NPC break + MAF + VF + MEM | NPC recovery ≥ 8.25 cm BAF ≤ 8.25 cpm NPC break ≥ 5.35 cm MAF ≤ 8.25 cpm VF ≤ 14.75 cpm MEM ≤ 0.63 D |
0.31 (0.11–0.50) |
1 (0.97–1) |
NA | 0.69 (0.54–0.92) |
| NPC recovery + BAF +NPC break + MAF +VF + MEM + NRA | NPC recovery ≥ 8.25 cm BAF ≤ 8.25 cpm NPC break ≥ 5.35 cm MAF ≤ 8.25 cpm VF ≤ 14.75 cpm MEM ≤ 0.63 D NRA ≤ 2.38 D |
0.27 (0.08–0.46) |
1 (0.97–1) |
NA | 0.73 (0.58–0.95) |
LR+: positive likelihood ratio, LR−: negative likelihood ratio, CI: confidence interval, NPC: near point of convergence, BAF: binocular accommodative facility, MAF: monocular accommodative facility, VF: vergence facility, MEM: monocular estimated method, NRA: negative relative accommodation, cpm: cycles per minute, D: diopter. NA: not applicable as the value tends to infinity.