Table 4.
Mean Network Measures in Controls (CTL) and Alzheimer's Disease Subjects
| |
CTL |
AD |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| NOD | λ | EFF | γ | SW | NOD | λ | EFF | γ | SW | |
| WB | 19.78 | 0.29 | 0.27 | 2.03 | 7.08 | 15.22 | 0.23 | 0.20 | 2.30 | 10.38 |
| LH | 16.00 | 0.49 | 0.43 | NS | 2.80 | 12.59 | 0.39 | 0.33 | NS | 3.60 |
| RH | 15.54 | 0.47 | 0.42 | NS | 2.90 | 12.66 | 0.39 | 0.34 | NS | 3.57 |
The mean nodal degree, normalized characteristic path length and efficiency decreased significantly between controls and AD subjects in all analyses. The normalized clustering coefficient increased in the whole brain of AD, while the normalized small-world effect increased in AD in all analyses, relative to controls. Mean values were rounded off to the nearest hundredth.
NOD, global nodal degree; λ, normalized characteristic path length; EFF, efficiency; γ, normalized clustering coefficient; SW, normalized small-world effect; WB, whole brain; LH, left hemisphere; RH, right hemisphere; NS, not significant.