Table 5.

Differences in Fiber Networks for the Whole Brain, Left, and Right Hemispheres Between Controls (CTL) and Alzheimer's Disease Subjects

	Network measures
CTL vs. AD(p-values)	NOD	λ	EFF	γ	SW
WB	3.86E-05	3.86E-05	4.02E-05	0.0038	9.06E-06
LH	2.91E-04	2.89E-04	3.08E-04	NS	2.99E-03
RH	1.51E-04	1.47E-04	1.85E-04	NS	9.03E-04

p-Values are shown, based on fitting a random effects model to the network measures (degree, normalized characteristic path length, efficiency, normalized clustering coefficient and normalized small-world) applied on the k-core (k=18) to test for diagnostic group differences between controls and AD subjects in the whole brain, left hemisphere, and then separately in the right hemisphere (with controls coded as 0 and AD subjects coded as 1). We covaried for age and sex and used acquisition site as a random regression variable.