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. Author manuscript; available in PMC: 2013 Aug 22.
Published in final edited form as: Nat Genet. 2010 Oct 17;42(11):985–990. doi: 10.1038/ng.694

Figure 3.

Figure 3

Statistical interaction between ERAP1 and HLA-C genotypes.

Odds ratio estimates for ERAP1 genotypes at rs27524 stratified by HLA-C genotypes at rs10484554. Odds ratios were estimated by fitting a logistic regression model which included the first principal component as a covariate and a parameter for each of the possible two-locus genotypes. Note that odds are measured relative to the most protective two-locus genotype (which by definition has an odds ratio of 1). Bars represent 95% confidence intervals calculated from the standard error of the estimates of the genotype parameters in logistic regression model.