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| Low (-1) | Medium (0) | High (+1) | |
|---|---|---|---|
| A- Drug Concentration |
2.5 mg |
5.0 mg |
7.5 mg |
| B- PLGA Concentration |
25 mg |
50 mg |
75 mg |
| C- PVA Concentration |
0.50% |
1.00% |
1.50% |
| D- Sonication Time | 30 Sec | 60 Sec | 90 Sec |
| Dependent variables | |||
|---|---|---|---|
| Y1- Percent Drug Entrapment (PDE) |
|
|
|
| Y2- Particle Size (PS) |
