Table I.
Combined SCOPE |
Adelaide SCOPE |
Auckland SCOPE |
ADE versus AUK |
||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Uncomplicated | SGA | P | Uncomplicated | SGA | P | Uncomplicated | SGA | P | Uncomplicated | SGA | |
n = 1185 | n = 216 | n = 427 | n = 109 | n = 758 | n = 107 | P | P | ||||
Maternal characteristics | |||||||||||
Age (years)a | 28.2 (5.6) | 28.5 (6.2) | 0.5 | 23.6 (5.0) | 24.3 (5.3) | 0.1 | 30.8 (4.1) | 32.7 (3.8) | <0.001 | <0.001 | <0.001 |
BMI (kg/m2)a | 24.9 (4.5) | 26.1 (5.5) | 0.003 | 26.0 (5.6) | 27.5 (6.2) | 0.01 | 24.3 (3.7) | 24.7 (4.3) | 0.3 | <0.001 | <0.001 |
sBP (mmHg)a | 106.2 (9.9) | 109.5 (11.1) | <0.001 | 107.9 (8.9) | 111.6 (11.2) | 0.002 | 105.3 (10.3) | 107.5 (10.8) | 0.05 | <0.001 | 0.006 |
dBP (mmHg)a | 63.3 (7.6) | 66.0 (8.9) | <0.001 | 63.5 (7.5) | 66.0 (8.9) | 0.007 | 63.2 (7.7) | 66.1 (8.9) | 0.002 | 0.5 | 1.0 |
Socioeconomic index (%) | |||||||||||
≥34 | 735 (62.0) | 104 (48.1) | <0.001 | 80 (18.7) | 9 (8.3) | 0.009 | 655 (86.4) | 95 (88.8) | 0.7 | <0.001 | <0.001 |
<34 | 450 (38.0) | 112 (51.9) | 347 (81.3) | 100 (91.7) | 103 (13.6) | 12 (11.2) | |||||
PPGLV (%) | |||||||||||
≥1 serve/day | 615 (51.9) | 92 (42.6) | 0.012 | 120 (28.1) | 25 (22.9) | 0.3 | 495 (65.3) | 67 (62.6) | 0.6 | <0.001 | <0.001 |
<1 serve/day | 570 (48.1) | 124 (57.4) | 307 (71.9) | 84 (77.1) | 263 (34.7) | 40 (37.4) | |||||
Smoking (%)a | |||||||||||
Non-smokers | 1074 (90.6) | 166 (76.9) | <0.001 | 337 (78.9) | 61 (56.0) | <0.001 | 737 (97.2) | 105 (98.1) | 1.0 | <0.001 | <0.001 |
Smokers | 111 (9.4) | 50 (23.1) | 90 (21.1) | 48 (44.0) | 21 (2.8) | 2 (1.9) | |||||
Gestational age at birth (weeks)b | 39.9 (1.9) | 39.7 (2.1) | 0.4 | 39.5 (1.9) | 39.4 (2.3) | 0.6 | 40.0 (1.8) | 40.1 (1.7) | 0.9 | <0.001 | 0.02 |
Maternal birthweight (g)c | 3335 (530) | 3167 (527) | <0.001 | 3287 (549) | 3136 (544) | 0.01 | 3361 (517) | 3197 (511) | 0.003 | 0.02 | 0.4 |
Paternal characteristics | |||||||||||
Age (years) | 30.7 (6.3) | 31.1 (6.7) | 0.5 | 26.4 (6.1) | 27.6 (6.3) | 0.054 | 33.2 (4.9) | 34.6 (5.0) | 0.005 | <0.001 | <0.001 |
Height (cm)d | 179.6 (6.7) | 177.6 (6.9) | <0.001 | 178.5 (6.7) | 176.3 (7.2) | 0.002 | 180.3 (6.7) | 179.0 (6.4) | 0.06 | <0.001 | 0.005 |
BMI (kg/m2)d | 26.6 (4.0) | 27.2 (4.6) | 0.07 | 26.9 (5.0) | 27.3 (5.0) | 0.4 | 26.4 (3.3) | 27.1 (4.1) | 0.1 | 0.07 | 0.7 |
Paternal birthweight (g)e | 3488 (571) | 3314 (521) | <0.001 | 3462 (593) | 3347 (558) | 0.09 | 3502 (559) | 3283 (485) | <0.001 | 0.2 | 0.4 |
Newborn characteristics | |||||||||||
Gestational age at birth (days) | 280.7 (8.1) | 271.6 (24.5) | <0.001 | 280.6 (8.0) | 271.9 (23.2) | <0.001 | 280.7 (8.1) | 271.4 (25.9) | <0.001 | 0.8 | 0.9 |
Body lengthf (cm) | 51.0 (2.2) | 47.1 (4.5) | <0.001 | 50.0 (1.8) | 46.2 (3.9) | <0.001 | 51.5 (2.2) | 48.0 (4.8) | <0.001 | <0.001 | 0.003 |
Head circumferencef (mm) | 35.2 (1.3) | 32.9 (2.5) | <0.001 | 34.9 (1.3) | 32.8 (2.3) | <0.001 | 35.3 (1.4) | 32.9 (2.8) | <0.001 | 0.001 | 0.7 |
Mid-arm circumferencef (mm) | 11.0 (0.9) | 9.4 (1.1) | <0.001 | 11.0 (0.9) | 9.2 (1.2) | <0.001 | 11.1 (0.9) | 9.5 (1.0) | <0.001 | 0.2 | 0.2 |
Birthweightf (g) | 3591 (394) | 2587 (560) | <0.001 | 3575 (390) | 2554 (536) | <0.001 | 3600 (396) | 2621 (583) | <0.001 | 0.3 | 0.4 |
Customized birthweight centile | 53.7 (25.0) | 4.6 (2.9) | <0.001 | 53.9 (24.9) | 4.0 (2.8) | <0.001 | 53.6 (25.1) | 5.1 (2.9) | <0.001 | 0.9 | 0.004 |
Sex of babies (%) | |||||||||||
Males | 601 (50.7) | 107 (49.5) | 0.8 | 210 (49.2) | 49 (45.0) | 0.4 | 391 (51.6) | 58 (54.2) | 0.7 | 0.4 | 0.2 |
Females | 584 (49.3) | 109 (50.5) | 217 (50.8) | 60 (55.0) | 367 (48.4) | 49 (45.8) |
Data are presented as the mean (SD) or n (%). sBP, systolic blood pressure; the second measurement; dBP, diastolic blood pressure; the second measurement; PPGLV, pre-pregnancy green leafy vegetable intake; 15 weeks, 15 weeks' gestation; ADE, Adelaide; AUK, Auckland. Italic values indicate significant difference.
aMeasurements were taken at 15 weeks' gestation.
bNumbers for women's gestational age at birth were 1166, 208, 419, 105, 747 and 103, for each group, respectively.
cNumbers for women's birthweight were 1153, 208, 411, 104, 742 and 104, for each group, respectively.
dNumbers for partner's height or BMI were 1157, 210, 422, 108, 735 and 102 for each group, respectively.
eNumbers for partner's birthweight were 1107, 197, 385, 94, 722 and 103 for each group, respectively.
fAdjusted for gestational age at birth.