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. 2013 Apr 29;19(9):570–580. doi: 10.1093/molehr/gat033

Table I.

Relevance of SFK/phosphatase pathway for sperm motility.

VAP VCL VSL ALH LIN STR
NC 28.5 ± 5.0* 57.0 ± 6.9* 19.0 ± 5.0* 3.6 ± 0.5 21.3 ± 4.4* 61.5 ± 5.7*
C 55.0 ± 1.8 83.0 ± 3.7 48.3 ± 1.4 4.5 ± 0.1 54.3 ± 1.3 85.0 ± 1.7
OA 40.2 ± 6.0 66.3 ± 5.7 34.1 ± 5.7 4.7 ± 0.8 46.5 ± 4.9 77.8 ± 3.1
SKI 23.7 ± 2.2* 50.0 ± 2.6* 14.5 ± 2.1* 3.8 ± 0.1* 28.5 ± 2.9* 59.3 ± 2.4*
SKI-OA 40.1 ± 4.7 65.9 ± 5.2 34.2 ± 5.0 3.9 ± 0.3 47.8 ± 4.3 78.3 ± 3.3

CASA analysis was performed on sperm incubated under non-capacitating (NC) or capacitating conditions in the absence (C) or presence of 30 μM SKI606 and/or 100 nM OA (SKI, OA or SKI-OA) for 18 h. Values represent the mean ± SEM of four independent experiments. VAP, average path velocity; VCL, curvilinear velocity; VSL, straight line velocity; ALH, amplitude of lateral head displacement; LIN, linearity; STR, straightness.

*versus C, P < 0.05.