Table 2.

Correlation between changes of cholesterol synthesis and absorption markers with changes of plasma lipids and apolipoprotein B levels after 6 weeks of ezetimibe add-on therapy

Parameter	Changes in lathosterol				Changes in β-sitosterol
	All	Low potency	Medium potency	High potency	All	Low potency	Medium potency	High potency

changes in Total C	0.339 ^**	0.203 ^*	0.291 ^**	0.646 ^**	0.260 ^**	0.364 ^**	0.229 ^**	0.217 ^*
changes in LDL-C	0.288 ^**	0.146	0.240 ^**	0.601 ^**	0.245 ^**	0.346 ^**	0.207 ^**	0.208 ^*
changes in Triglycerides	0.164 ^**	0.149	0.161 ^**	0.220 ^*	0.073 ^*	0.043	0.057	0.144
changes in HDL-C	0.022	−0.068	0.039	0.016	0.061	0.003	0.103 ^*	−0.033
changes in Total C/HDL-C	0.241 ^**	0.204 ^*	0.186 ^**	0.485 ^**	0.170 ^**	0.207 ^*	0.133 ^*	0.177 ^*
changes in Non-HDL-C	0.338 ^**	0.216 ^*	0.288 ^**	0.641 ^**	0.250 ^**	0.359 ^**	0.210 ^**	0.222 ^*
changes in Apo B	0.311 ^**	0.131	0.274 ^**	0.610 ^**	0.218 ^**	0.258 ^*	0.189 ^**	0.191 ^*

Parameter	Changes in lathosterol/cholesterol				Changes in β-sitosterol/cholesterol
	All	Low potency	Medium potency	High potency	All	Low potency	Medium potency	High potency

changes in Total C	0.103 ^*	−0.066	0.076	0.382 ^**	−0.079 ^*	0.077	−0.071	−0.229 ^*
changes in LDL-C	0.086 ^*	−0.099	0.065	0.354 ^**	−0.064	0.085	−0.052	−0.229 ^*
changes in Triglycerides	0.068 ^*	0.126	0.058	0.111	−0.043	−0.026	−0.067	0.016
changes in HDL-C	−0.024	−0.139	−0.012	−0.005	0.029	0.018	0.059	−0.063
changes in Total C/HDL-C	0.076 ^*	0.069	0.033	0.290 ^**	−0.061	0.001	−0.075	−0.107
changes in Non-HDL-C	0.109 ^*	−0.036	0.080	0.381 ^**	−0.086 ^*	0.072	−0.086	−0.217 ^*
changes in Apo B	0.106 ^**	−0.090	0.088 ^*	0.374 ^**	−0.093 ^*	0.002	−0.085 ^*	−0.231 ^*

Values are expressed as correlation coefficients

p ≤0.05;

^**

p <0.001