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. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: Cancer Res. 2012 Jun 27;72(17):4472–4482. doi: 10.1158/0008-5472.CAN-12-0057

Figure 4. Lifespan of eNOS-/- and L-NAME-treated KPC mice.

Figure 4

(A) Kaplan-Meier survival curve of cohorts of KPC mice untreated (n=35) or treated with L-NAME (n=32) and eNOS-/- KPC mice (n=32). (B) mean size ± SEM of subcutaneous xenograft tumors generated by a cell line derived from a KPC adenocarcinoma injected in isogenic immunocompetent cohorts of mice randomly assigned to either be untreated (n=4) or treated with L-NAME (n=4). *P<0.05. One L-NAME treated mouse was euthanized at day 29 for reasons unrelated to tumor size.