Table III.
Odds ratios of congenital anomalies with 95% confidence intervals in data matched between Congenital Malformation Registry and New York State newborn screening database
| Congenital anomalies | CHT (n = 1538) | Non-CHT (n = 3 654 033) | OR (95% CI) |
|---|---|---|---|
| Renal | |||
| Dysplastic kidney | 10 | 629 | 38.0 (20.3-71.1) |
| Renal agenesis | 4 | 1631 | 5.8 (2.2-15.6) |
| Ectopic kidney | 2 | 632 | 7.5 (1.9-30.2) |
| Hydronephrosis | 30 | 8055 | 8.7 (6.0-12.6) |
| Hydroureter | 1 | 564 | 4.2 (0.6-29.9) |
| Atresia/Stenosis of ureter | 1 | 135 | 17.6 (2.5-126) |
| Hypospadias | 1 | 14 585 | 0.16 (0.02-1.2) |
| Anterior urethral obstruction | 1 | 31 | 76.7 (10.5-562.1) |
| UPJ obstruction | 4 | 691 | 13.8 (5.2-36.9) |
| Composite OR | 53 | 26 953 | 4.8 (3.7-6.3) |
| Cardiovascular | |||
| Atrial septal defect | 37 | 10 619 | 8.5 (6.1-11.7) |
| Ventricular septal defect | 44 | 13 401 | 8.0 (5.9-10.8) |
| Coarctation of aorta | 8 | 1501 | 15.9 (8.5-29.7) |
| Tetralogy of Fallot | 8 | 1684 | 11.3 (5.7-22.8) |
| Endocardial cushion defect | 10 | 1135 | 21.1 (11.3-39.3) |
| Composite OR | 109 | 28 340 | 9.8 (8.0-11.9) |
| Gastrointestinal | |||
| Duodenal atresia/stenosis | 4 | 586 | 16.1 (6.1-43.5) |
| Oral clefts | 4 | 4723 | 2.0 (0.8-5.4) |
| Pyloric stenosis | 3 | 6261 | 1.1 (0.4-3.5) |
| Composite OR | 11 | 11 570 | 2.3 (1.3-4.1) |
| Skeletal | |||
| Craniosynostosis | 1 | 1464 | 1.6 (0.2-11.5) |