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. 2013 May 23;22(18):3807–3817. doi: 10.1093/hmg/ddt231

Table 2.

Association results for SNPs that met P < 0.05 after permutation in the analysis of craniofacial size and shape

Traita Marker Gene/locus Alleles Frequency of A1 RSQR Effect SE P-value Permuted P-value
Width of eye region
 psL-psR: left-to-right palpebrale superius distance rs17101923 HMGA2 G/T 0.78 0.9645 0.11 0.028 0.00011 0.0042
 piL-piR: left-to-right palpebrale inferius distance rs17101923 HMGA2 G/T 0.78 0.9645 0.109 0.028 0.00012 0.0049
 exR.yz: distance of the right exocanthion from the YZ plane rs17101923 HMGA2 G/T 0.78 0.9645 0.099 0.028 0.00043 0.018
 enL.yz: distance of the left endocanthion from the YZ plane rs17101923 HMGA2 G/T 0.78 0.9645 0.096 0.028 0.00067 0.025
 enL-enR: left-to-right endocanthion distance rs17101923 HMGA2 G/T 0.78 0.9645 0.094 0.028 0.00074 0.028
 exL-exR: left-to-right exocanthion distance rs17101923 HMGA2 G/T 0.78 0.9645 0.093 0.028 0.00087 0.033
Width of lower part of nose
 prn-alL: pronasale to left alare distance rs17101923 HMGA2 G/T 0.78 0.9645 0.08 0.025 0.0013 0.044
 sn-alL: subnasale to left alare rs7924176 ADK VCL AP3M1 A/G 0.58 0.9714 0.071 0.022 0.0013 0.049
 alL-alR: left-to-right alare distance rs17101923 HMGA2 G/T 0.78 0.9645 0.078 0.024 0.0014 0.048
Height and prominence of the mid-brow
 g-men: glabella to mid-endocanthion distance rs997154 AJUBA G/A 0.23 0.9698 0.104 0.027 0.00016 0.0069

All alleles are on the forward strand. The effect allele is displayed in bold font and in each case is also the allele associated with increased the number of teeth at 12 months. Freq1 is the allele frequency of the effect allele.

aSee Supplementary Material Figure S4 for additional information on landmark positions.