Figure 9.
Change in the normalized RMS fluctuations of Cα atoms observed in the collective dynamics of the four mutants with respect to WT Ec ProRS. The angular bracket indicates that the RMS fluctuations are averaged over the first three clusters representing the predominant collective protein motions. The propagated uncertainties for each of these plots are within 0.15 Å and are shown with two parallel dotted lines. The abbreviations used are: CD, catalytic (aminoacylation) domain; INS, insertion domain; and ACB, anticodon binding domain.