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. Author manuscript; available in PMC: 2014 Jun 25.
Published in final edited form as: Biochemistry. 2013 Jun 17;52(25):4399–4412. doi: 10.1021/bi400079h

Table 1.

Number of conserved and co-evolved residues with in Ec ProRS that are engaged in correlated motion. These residue numbers were determined by varying cutoff values for ΔGistat (evolutionary conservation constant) and CDCij, ( CDCij=ΔΔGijstat×Cij; coevolutionary dynamic coupling constant), respectively, while maintaining the correlation coefficient of residue-residue fluctuations (Cij) greater than or equal to 0.8.

ΔGistat
≥ 0.50 ≥ 0.55 ≥ 0.60 ≥ 0.65 ≥ 0.70
Number of Conserved Residues 207 182 151 104 61
CDCij 0.40 0.45 0.50 0.55 0.60
Number of Co-evolved Residues 96 69 48 28 18