TABLE I.
Characteristics of patients with pulmonary tuberculosis (TB) who met the criteria for tuberculosis drug susceptibility testing (DST), Santos, Brazil, 2000–2004
| Underwent DST |
||||
|---|---|---|---|---|
| Yes (n = 213) | No (n = 458) | Total (n = 671) | ||
| Characteristics | n (%) | n (%) | n (%) | p |
| Gender | 0.23 | |||
| Female | 57 (27.4) | 143 (31.2) | 200 (29.8) | - |
| Male | 156 (73.2) | 315 (68.8) | 471 (70.2) | - |
| Age (years) | ||||
| 15–19 | 4 (1.9) | 10 (2.2) | 14 (2.1) | 0.76 |
| 20–49 | 167 (78.4) | 368 (80.3) | 535 (79.7) | - |
| 50 or more | 42 (19.7) | 80 (17.5) | 122 (18.2) | - |
| Schooling | 0.28 | |||
| Up to 7 years | 61 (34.7) | 162 (44.6) | 223 (41.4) | - |
| 8 years or more | 115 (65.3) | 201 (55.4) | 316 (58.6) | - |
| Alcohol dependence | 0.14 | |||
| No | 166 (83) | 379 (87.7) | 545 (86.2) | - |
| Yes | 34 (17) | 53 (12.3) | 87 (13.8) | - |
| HIV infection | < 0.0003 | |||
| No | 127 (60.8) | 194 (43.7) | 321(49.2) | - |
| Yes | 82 (39.2) | 250 (56.3) | 332 (50.8) | - |
| Past history of TB | 0.25 | |||
| No | 86 (40.4) | 161 (37.1) | 247 (38.2) | - |
| Yes | 127 (59.6) | 273 (62.9) | 400 (61.8) | - |
| Outcome of prior TB treatment | 0.57 | |||
| Cure | 45 (35. 7) | 114 (41.8) | 159 (39.8) | - |
| Dropout | 81 (64. 3) | 159 (58.2) | 240 (60.2) | - |
| Relapse | 0.27 | |||
| No | 169 (82) | 300 (76.0) | 499 (78) | - |
| Yes | 37 (18) | 104 (24.0) | 141 (22) | - |
| Cavitary pulmonary lesions | < 0.0001 | |||
| No | 128 (68.1) | 331 (84.9) | 459 (79.4) | - |
| Yes | 60 (31.9) | 59 (15.1) | 119 (20.6) | - |
| Treatment regimen | < 0.0001 | |||
| Unchanged | 173 (87.8) | 422 (96.6) | 595 (93.8) | - |
| Changed | 24 (12.2) | 15 (3.4) | 39 (6.2) | - |
| Treatment completion | ||||
| Cure | 127(67.2) | 255 (62.3) | 382 (63.9) | 0.24 |
| Unfavourable outcomea | 63 (32.8) | 154 (37.7) | 217 (36.1) | - |
a
dropout, deaths from TB and acquired immune deficiency syndrome, treatment failure;
HIV: human immunodeficiency virus.
Inconsistencies between total patients studied and total variables are due to missing information.