Table 1.
Vγ4 |
|||||||
---|---|---|---|---|---|---|---|
V | N | J | Frequency | In Frame | |||
Canonical | EATYYCACW | DSSGF | 48/50 | Yes | |||
EATYYCAW | DSSGF | 1/50 | No | ||||
EATYYCACW | YSSGF | 1/50 | Yes |
Vδ1 |
|||||||
---|---|---|---|---|---|---|---|
V | N | D1 | N | J | Frequency | In Frame | |
Canonical | GTYYCGSD | IGG | SSWDTR | 21/30 | Yes | ||
Non-canonical | GTYYCGSD | IGG | IRA | TDKLVF | 3/30 | Yes | |
GTYYCGSD | I | VGG | IRA | TDKLVF | 1/30 | Yes | |
GTYYCGSD | IGG | T | TDKLVF | 1/30 | Yes | ||
GTYYCGSD | RRD | T | TDKLVF | 1/30 | Yes | ||
GTYYCGSD | M | G | YELVF | 1/30 | Yes | ||
GTYYCGSD | I | SEG | Y | LPTNSSL | 1/30 | No | |
GTYYCGSD | IGG | IPTNSSL | 1/30 | No |
Vγ4 and Vδ1 sequences were determined from sorted CD27neg CD44high γδ T cells from MLNs of mice infected 9 days previously. Canonical and non-canonical Vγ4 and Vδ1 TCR amino acid junctional sequences are displayed in reference to their frequency and in frame translation. Dashed line separates sequences that contain distinct J regions. Data in table is a compilation of sequences obtained from two independent experiments.