Table 1.
Body composition and serum insulin in members of leptin-injected or vehicle-injected pairs of ob/ob mice.
Leptin-injected Parabiont | Partner of leptin-injected | Member of vehicle injected pair | |
---|---|---|---|
Preoperative wt (g) | 43 ± 2 | 42 ± 2 | 42 ± 1 |
Carcass wt (g) | 33 ± 2A | 37 ± 1B | 40 ± 1C |
Carcass fat (g) | 16.0 ± 1.3A | 19.0 ± 0.9B | 23.3 ± 0.7C |
Calculated food intake (mg/24 hr) | 443 ± 299A | 882 ± 260A | 1101 ± 162B |
Serum insulin (ng/ml) | 1.1 ± 0.3A | 1.6 ± 0.3A | 14.0 ± 1.7B |
Data are means ± sem for mice from 5 pairs of leptin-injected ob/ob mice or 4 pairs of vehicle injected ob/ob mice. Values for a specific parameter that do not share a common superscript are significantly different at P<0.05. Mice received twice daily i.p. injections of 50 ug human recombinant leptin or vehicle for 11 days (Harris, Zhou, Weigle, & Kuijper, 1997)