Figure 2. Comparison of the gene content of S. lophii to published microsporidian genomes.

A. Phylogenetic distribution of annotated S. lophii proteins. Gene families (OrthoMCL clusters) were mapped on to a multigene phylogeny of microsporidia and their opisthokont relatives (see also Figure 7A.). B. Graphical illustration of the variation in fatty acid synthesis enzymes encoded by six different microsporidian genomes. Although the S. lophii genome is larger than that of E. cuniculi, it has lost some components of the pathway that are conserved in the smaller genome, such as isoprenoid biosynthesis. Reference numbers are given for E. cuniculi or S. lophii locus ID's.