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. 2013 Aug 22;9(8):e1003585. doi: 10.1371/journal.pgen.1003585

Figure 4. LD plot among common and low-frequent SNPs in the SERPINA1 gene within the SAPALDIA study.

Figure 4

Shading represent r2 values, whereas numbers represent D′ values (no number equals D′ = 1). Red framed SNPs are independently associated with AAT serum levels after forward selection stepwise regression modeling. Rs17580 is the PI S variant and rs28929474 is the PI Z variant.