Table 3. Minor allele effects of PI S, PI Z and rs4905179 on AAT serum levels in the Copenhagen City Heart Study.
SNP | N | MAF (genotyped) | Allele Effect (g/L) | 95% Confidence Intervals | P |
rs17580 (PI S) | 8338 | 0.029 | −0.188 | −0.211 to −0.165 | <0.0001 |
rs28929474 (PI Z) | 8338 | 0.027 | −0.492 | −0.514 to −0.470 | <0.0001 |
rs4905179 | 8332 | 0.186 | −0.097 | −0.107 to −0.087 | <0.0001 |
rs4905179, adjusted for PI S and Z | 8273 | 0.186 | 0.003 | −0.007 to 0.013 | 0.57 |
Abbreviations: MAF, minor allele frequency; SNP, single nucleotide polymorphism.