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. 2013 Aug 22;9(8):e1003585. doi: 10.1371/journal.pgen.1003585

Table 3. Minor allele effects of PI S, PI Z and rs4905179 on AAT serum levels in the Copenhagen City Heart Study.

SNP N MAF (genotyped) Allele Effect (g/L) 95% Confidence Intervals P
rs17580 (PI S) 8338 0.029 −0.188 −0.211 to −0.165 <0.0001
rs28929474 (PI Z) 8338 0.027 −0.492 −0.514 to −0.470 <0.0001
rs4905179 8332 0.186 −0.097 −0.107 to −0.087 <0.0001
rs4905179, adjusted for PI S and Z 8273 0.186 0.003 −0.007 to 0.013 0.57

Abbreviations: MAF, minor allele frequency; SNP, single nucleotide polymorphism.