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. 2013 Aug 22;9(8):e1003716. doi: 10.1371/journal.pgen.1003716

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© 2013 Wiles et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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To orient the reader to graph organization and symbols, a key is provided in the lower right corner. The cumulative percent of genes (y-axis) within each Tn-seq-derived gene set (x-axis) belonging to the functional categories (A) informational, (B) RNA (C) environmental interactions, (D) cellular processes, (E) metabolism and (F) hypothetical is depicted. The proportion of genes contributed by specific sub-KEGG categories is represented by stacked elements within each column. Significant enrichments for KEGG and sub-KEGG categories are denoted with asterisks and white circles, respectively. Gene set abbreviations: hypo-tol. = hypo-tolerant; hyper-tol. = hyper-tolerant; advant. = advantageous. Theoretical KEGG category compositions for Tn-seq gene sets and p values were determined using 10,000 Monte Carlo simulations (Methods).