Table 7. Frequency of Cx43, Cx47 and Cx32 immunoreactivity patterns in demyelinating lesions from cases with MS.

	MS (n=51)				MS (n=51)
Cx43 expression pattern	Active (n=24)	Chronic active (n=17)	Chronic inactive (n=10)	Cx47 and Cx32 expression pattern	Active (n=24)	Chronic active (n=17)	Chronic inactive (n=10)
Pattern A	7	4	0	Pattern A	0	2	2
Pattern B	8	3	0	Pattern B	14	13	8
Pattern C	1	1	1	Pattern C	2	2	0
Pattern D	3	9	9	Pattern D	0	0	0
Pattern N	5	0	0	Pattern N	5	0	0

See Table 3 for the pattern definitions. Any pattern with necrosis (pattern X & N) was included as pattern X.

Cx = connexin, MS = multiple sclerosis, NMO = neuromyelitis optica, NMOSD = neuromyelitis optica spectrum disorder