Figure 2. Salt-exposed offspring have increased blood pressure throughout the circadian cycle.

For blood pressure, assessed by telemetry, data are from Control diet; n = 6 dams, n = 6/6 [male/female] offspring or high-salt (4% salt) diet; n = 6 dams, n = 5/5 [male/female] offspring. Values are either hourly means (A,B; derived from summary measures of 48 h recording) or the fitted model from non-linear regression [Fourier] analysis of all datapoints recorded over the 48 h period (C,D) and the respective output of circadian parameters from the model (E). Data are predicted means (±S.E.M.) and were analysed by mixed effect models with treatment (control vs. 4% salt) and sex (male vs. female) or their interaction as fixed and dam as a random effect (Genstat v14). NS, not significant.