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. 2013 Aug 22;8(8):e72682. doi: 10.1371/journal.pone.0072682

Table 2. Maternal salt diet has little effect on feto-placental tissues in late gestation.

Tissue composition of feto-placental unit ay day 20 and term (day 21)
± Maternal salt P value
Males Age −ve +ve s.e.d. Salt Age Salt*Age
Fetal wet weight (g) d20 3.51 3.58 0.20 NS <.001 NS
term 5.49 5.67
Placental wet weight (mg) d20 527 547 36 NS - -
term - -
% water in fetus d20 84.2 87.1 1.6 NS 0.02 NS
term 81.8 82.9
% water in placenta d20 84.4 85.4 0.62 NS NS NS
term - -
Females
Fetal wet weight (g) d20 3.50 3.49 0.20 NS <.001 NS
term 5.54 5.49
Placental wet weight (mg) d20 493 527 36 NS - -
term - -
% water in fetus d20 85.0 86.6 1.6 NS 0.02 NS
term 83.2 83.0
% water in placenta d20 84.8 85.2 0.62 NS NS NS
term - -

Data are estimated marginal means plus the standard error of the differences between means (s.e.d.). At day 20, data are n = 10 dams per dietary group (Control, n = 4 male/female pups; 4% salt diet n = 7 male and n = 4 female pups). At term, data are n = 8 control and n = 5 SD dams (Control, n = 8/8 male/female pups; SD diet, n = 7/5 male/female pups). Data were analysed by mixed effects models with treatment (control vs. 4% salt), sex (male vs. female) and age (day 20 vs. term) or their interaction as fixed effects and dam as a random effect (Genstat v14). Log10 transformation was used before analysis, as required, to achieve normality in error distribution. NS, not significant. −ve, is control diet (CD). +ve, is 4% salt diet (SD).