Table 2. Maternal salt diet has little effect on feto-placental tissues in late gestation.
Tissue composition of feto-placental unit ay day 20 and term (day 21) | |||||||
± Maternal salt | P value | ||||||
Males | Age | −ve | +ve | s.e.d. | Salt | Age | Salt*Age |
Fetal wet weight (g) | d20 | 3.51 | 3.58 | 0.20 | NS | <.001 | NS |
term | 5.49 | 5.67 | |||||
Placental wet weight (mg) | d20 | 527 | 547 | 36 | NS | - | - |
term | - | - | |||||
% water in fetus | d20 | 84.2 | 87.1 | 1.6 | NS | 0.02 | NS |
term | 81.8 | 82.9 | |||||
% water in placenta | d20 | 84.4 | 85.4 | 0.62 | NS | NS | NS |
term | - | - | |||||
Females | |||||||
Fetal wet weight (g) | d20 | 3.50 | 3.49 | 0.20 | NS | <.001 | NS |
term | 5.54 | 5.49 | |||||
Placental wet weight (mg) | d20 | 493 | 527 | 36 | NS | - | - |
term | - | - | |||||
% water in fetus | d20 | 85.0 | 86.6 | 1.6 | NS | 0.02 | NS |
term | 83.2 | 83.0 | |||||
% water in placenta | d20 | 84.8 | 85.2 | 0.62 | NS | NS | NS |
term | - | - |
Data are estimated marginal means plus the standard error of the differences between means (s.e.d.). At day 20, data are n = 10 dams per dietary group (Control, n = 4 male/female pups; 4% salt diet n = 7 male and n = 4 female pups). At term, data are n = 8 control and n = 5 SD dams (Control, n = 8/8 male/female pups; SD diet, n = 7/5 male/female pups). Data were analysed by mixed effects models with treatment (control vs. 4% salt), sex (male vs. female) and age (day 20 vs. term) or their interaction as fixed effects and dam as a random effect (Genstat v14). Log10 transformation was used before analysis, as required, to achieve normality in error distribution. NS, not significant. −ve, is control diet (CD). +ve, is 4% salt diet (SD).