Figure 1. HER2 tumour levels and classification of HER2 amplified and non-amplified cancers.
A) Relative mRNA expression levels of HER2 in estrogen receptor positive (ER+; black bars) and ER negative (- ; white bars with asterisk) breast tumours from pre- and postmenopausal women. Tumours identified to be HER2 non-amplified (NA) and amplified (A) by MPLA are indicated. B) Relative HER4 levels in HER2 NA and A tumours. Significant difference between A and NA tumours is presented using the Mann-Whitney U test.