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. 2013 Aug 22;8(8):e74618. doi: 10.1371/journal.pone.0074618

Table 2. Patient and tumour characteristics.

Premenopausal (n = 13) Postmenopausal (n = 29a)
Median age (range), y 41 (31-49) 61 (44-81)
IHC ER, n ER+ 7 20
ER- 6 9
IHC PR, n PR+ 7 17
PR- 6 12
MLPA, EGFR/HER1, n Ampl* 0 1
Non-ampl 13 25
MLPA, HER2, n Amplb 5 4
Non-ampl 8 22

Abbreviations: IHC, Immunohistochemistry; ER, estrogen receptor; PR, progesterone receptor

a Normal tissue was not available for MLPA and mRNA analyses from one patient and tumour tissues were not available from two other patients

b More than 2 alleles of either HER2 or EGFR were considered amplified.