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. 2013 Aug 22;8(8):e72049. doi: 10.1371/journal.pone.0072049

Table 4. Factors associated with fatty liver in different populations by multivariate analysis.

Odds ratio 95% confidence interval P
All subjects
BMI (per kg/m2) 1.209 1.191–1.227 <0.001
Age (per years) 1.004 1.002–1.006 0.001
WC (per cm) 1.036 1.031–1.042 <0.001
SBP (per mmHg) 1.002 1.000–1.003 0.040
Fasting glucose (per mg/dL) 1.010 1.009–1.011 <0.001
Cholesterol (per mg/dL) 1.008 1.007–1.009 <0.001
HDL (per mg/dL) 0.969 0.967–0.971 <0.001
ALT (per U/L) 1.018 1.016–1.020 <0.001
Platelet (per/mm3) 1.002 1.002–1.003 <0.001
HBsAg 0.700 0.642–0.764 <0.001
For subjects with HBV infection
BMI (per kg/m2) 1.161 1.110–1.214 <0.001
WC (per cm) 1.055 1.038–1.072 <0.001
Fasting glucose (per mg/dL) 1.013 1.009–1.017 <0.001
Cholesterol (per mg/dL) 1.006 1.003–1.008 <0.001
HDL (per mg/dL) 0.973 0.967–0.979 <0.001
ALT (per IU/L) 1.003 1.001–1.005 0.003
Platelet (per/mm3) 1.003 1.002–1.004 <0.001
For subjects with BMI≤22.4 kg/m2
Age (per years) 1.005 1.001–1.009 0.02
WC (per cm) 1.071 1.062–1.080 <0.001
Fasting glucose (per mg/dL) 1.010 1.008–1.012 <0.001
Cholesterol (per mg/dL) 1.006 1.005–1.008 <0.001
HDL (per mg/dL) 0.977 0.973–0.981 <0.001
ALT (per IU/L) 1.007 1.005–1.009 <0.001
Platelet (per/mm3) 1.002 1.001–1.003 0.001
For subjects with BMI>22.4 kg/m2
Male gender 1.193 1.111–1.282 <0.001
WC (per cm) 1.068 1.063–1.073 <0.001
SBP (per mmHg) 1.003 1.002–1.005 <0.001
Fasting glucose (per mg/dL) 1.010 1.009–1.012 <0.001
Cholesterol (per mg/dL) 1.008 1.007–1.009 <0.001
HDL (per mg/dL) 0.964 0.961–0.966 <0.001
ALT (per IU/L) 1.025 1.023–1.027 <0.001
Platelet (per/mm3) 1.003 1.002–1.003 <0.001
HBsAg positivity 0.655 0.593–0.723 <0.001
For subjects with age≦50 years
BMI (per kg/m2) 1.176 1.147–1.204 <0.001
Male gender 0.817 0.736–0.907 <0.001
WC (per cm) 1.048 1.038–1.057 <0.001
SBP (per mmHg) 1.004 1.001–1.007 0.009
Fasting glucose (per mg/dL) 1.013 1.010–1.016 <0.001
Cholesterol (per mg/dL) 1.008 1.007–1.009 <0.001
HDL (per mg/dL) 0.972 0.968–0.976 <0.001
ALT (per IU/L) 1.011 1.009–1.014 <0.001
GGT (per IU/L) 1.003 1.001–1.004 <0.001
Platelet (per/mm3) 1.003 1.002–1.003 <0.001
For subjects with age >50 years
BMI (per kg/m2) 1.225 1.202–1.249 <0.001
Male gender 1.115 1.032–1.205 0.006
WC (per cm) 1.030 1.023–1.036 <0.001
Fasting glucose (per mg/dL) 1.009 1.008–1.011 <0.001
Cholesterol (per mg/dL) 1.007 1.006–1.008 <0.001
HDL (per mg/dL) 0.967 0.964–0.970 <0.001
ALT (per IU/L) 1.022 1.020–1.025 <0.001
Platelet (per/mm3) 1.003 1.002–1.003 <0.001
HBsAg positivity 0.624 0.553–0.703 <0.001

BMI, body mass index; WC, waist circumference; SBP, systolic blood pressure; HDL, high-density lipoprotein; ALT, alanine aminotransferase; GGT, gamma-glutamyltransferase; HBsAg, hepatitis B surface antigen.