Table 2. Number of candidate SNVs in 20 familial NSHL through five filtering steps.
| Patient | 1) basic filtering | 2) inheritance pattern | 3) Sanger sequencing | 4) Control | 5) Clinical feature | Final | |
| Segregation | Audiogram profile matching | ||||||
| ADNSHL | |||||||
| SB14-30 | 8 | 1 | 1 | 1 | - | 1 | 1 |
| SB40-77 | 6 | 3 | 3 | 2 | - | 0 | 0 |
| SB41-78 | 3 | 1 | 1 | 0 | - | - | 0 |
| SB50-94 | 3 | 2 | 1 | 1 | - | 1 | 1 |
| SB54-101 | 5 | 4 | 4 | 3 | 1 | 1 | 1 |
| SB55-102 | 1 | 0 | - | - | - | 0 | 0 |
| SB60-107 | 6 | 3 | 2 | 2 | 1 | 1 | 1 |
| SB61-109 | 4 | 2 | 2 | 1 | - | 1 | 1 |
| SH14-37 | 4 | 2 | 2 | 1 | 1 | 1 | 1 |
| SH20-47 | 5 | 1 | 1 | 1 | 1 | 1 | 1 |
| SH21-50 | 4 | 3 | 3 | 2 | 1 | 1 | 1 |
| SH40-89 | 6 | 5 | 5 | 5 | 2 | 1 | 1 |
| SH41-90 | 2 | 1 | 1 | 1 | 0 | 0 | 0 |
| ARNSHL | |||||||
| SB04-11 | 8 | 2 | 2 | 2 | 2 | 2 | 2 |
| SB38-75 | 4 | 2 | 2 | 2 | 2 | 2 | 2 |
| SB47-91 | 5 | 3 | 3 | 2 | - | 2 | 2 |
| SH10-28 | 5 | 2 | 1 | 1 | - | - | 0 |
| SH23-52 | 3 | 0 | 0 | - | - | - | 0 |
| SH27-61 | 7 | 0 | 0 | 0 | - | - | 0 |
| SH35-75 | 7 | 2 | 2 | 2 | - | ? | 2 |