Table 2.

Associations between selected single nucleotide polymorphisms and sleep outcomes.

	Insomnia				Early awakening
	Unadjusted model		Adjusted model		Unadjusted model		Adjusted model
	OR	95% CI	OR	95% CI	OR	95% CI	OR	95% CI
AHRR
CC	1.00	Referent	1.00	Referent	1.00	Referent	1.00	Referent
CG	0.75	0.54–1.04	0.69	0.49–0.96	1.01	0.73–1.39	1.02	0.73–1.43
GG	1.99	0.86–4.62	1.63	0.68–3.88	1.78	0.78–4.06	1.70	0.73–3.96
AHR
GG	1.00	Referent	1.00	Referent	1.00	Referent	1.00	Referent
GA	0.99	0.70–1.42	1.06	0.72–1.57	1.42	1.00–2.03	1.36	0.93–2.01
AA	1.95	0.93–4.12	2.19	0.99–4.85	1.38	0.66–2.90	1.32	0.61–2.85
ARNT
GG	1.00	Referent	1.00	Referent	1.00	Referent	1.00	Referent
CG	0.93	0.65–1.32	0.96	0.67–1.37	0.96	0.68–1.36	0.97	0.68–1.38
CC	0.83	0.52–1.32	0.85	0.53–1.38	1.00	0.63–1.60	0.97	0.61–1.56
CLOCK
TT	1.00	Referent	1.00	Referent	1.00	Referent	1.00	Referent
TC	0.78	0.56–1.08	0.75	0.54–1.06	0.94	0.68–1.30	0.96	0.69–1.34
CC	0.91	0.40–2.09	0.83	0.35–1.94	2.17	0.91–5.19	2.20	0.91–5.33

Abbreviations: OR, odds ratio; CI, confidence interval; AHHR, aryl hydrocarbon receptor repressor; AHR, aryl hydrocarbon receptor; ARNT, aryl hydrocarbon receptor nuclear translocator; CLOCK, circadian locomotor output cycles kaput.

Adjusted OR is adjusted for age (<50/50+ y), race, body mass index (≥30, 25–29, <25), and smoking status (never, former, current).