FIGURE 4. Honokiol attenuates CsA-induced proliferation of renal cancer cells.

(a) Caki-1 and (b) 786-O cells were treated with different combinations of 5 μg/ml CsA, 20 μM honokiol (HNK) or vehicle alone for 48 h. Cell proliferation was measured by MTT assay. Results are representative of three independent experiments. Columns, average of triplicate readings from three different samples; error bars, SEM. * p < 0.05 compared with vehicle treated control, and ** p < 0.05 compared with CsA-treated but HNK-untreated cells..