Figure 2.
Structure of MilB. (A) The MilB protomer structure adopts an overall α/β-twist fold, depicted with β-strands in green and α-helices in blue. (B) The topology diagram of MilB with β-strands in light green and α-helices in light blue. (C) The dimeric structure of MilB with chain A in green and chain B in cyan and ligands bound in the active sites. (D) The active site phosphate-binding pocket is occupied by a sulfate ion in the MilB/SO4 complex. The sulfate binding site corresponds to the phosphate binding site in the CMP complex.