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. Author manuscript; available in PMC: 2014 Sep 28.
Published in final edited form as: Cancer Lett. 2013 Apr 2;338(2):229–238. doi: 10.1016/j.canlet.2013.03.032

Fig. 4. Enforced expression of ectopic Mcl-1 in H1299 (A and B) or A549 cells (C and D) protects cells from BKM120-induced apoptosis.

Fig. 4

The indicated cell lines were exposed to 4 µM BKM120 for 24 h and then harvested for preparation of whole-cell protein lysates and subsequent Western blot analysis to detect caspase cleavage (A and C) and for detection of apoptosis (i.e., annexin V-positive cells) with flow cytometry (B and D). Pro-casp, pro-caspase; CF, cleaved from.