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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: J Immunol. 2013 Aug 5;191(5):2829–2836. doi: 10.4049/jimmunol.1202777

Figure 4. CD80-Fc restores PBMC activation more efficiently than antibodies to PDL1 or PD1.

Figure 4

PHA-activated PBMC from healthy human donors were co-cultured with human C8161 melanoma, H358 squamous cell carcinoma, or H292 bronchioloalveolar adenocarcinoma cells in the presence of CD80-Fc, antibodies to PDL1 or PD1, or control IgG1 and/or irrelevant fusion protein TROY-Fc. IFNγ production was measured by ELISA. Data are representative of 3 independent experiments for each cell line.