Fig. 8. Jaridonin reduced the MMP of EC9706 cells and antioxidants reversed the effect of Jaridonin on the MMP and cell growth.
A and B. EC9706 Cells were pretreated with or without 5mM L-NAC for 2 hours, and then incubated with Jaridonin for an additional 24 hours. The cells were stained with JC-1 and imaged by fluorescent microscopy. C and D. EC9706 or EC109 Cells were pretreated with or without 5mM L-NAC or Vit C for 2 hours, and then incubated with the indicated concentrations of Jaridonin for 24 hours. Cell viabilities were evaluated by MTT assay. **P<0.01 for Jaridonin versus control; ## P<0.01 for Jaridonin versus Jaridonin + antioxidants. Data are expressed as means ± SD. Each data point is an average of three independent experiments.