Skip to main content
. Author manuscript; available in PMC: 2013 Aug 22.
Published in final edited form as: Org Lett. 2008 May 14;10(12):2409–2412. doi: 10.1021/ol800675u

Table 1.

Reaction Optimizationa

graphic file with name nihms-489955-t0002.jpg

entry fluoride source solvent T (°C) time (h) yieldb (%)
1 TBAF THF 0 to rt 3 37
2 TBAF MeCN 0 to rt 3 45
3 TBAF DCM 0 to rt 5 34
4 CsF THF rt 18 37
5 CsF MeCN rt 18 76
a

All reactions were carried out on a 0.3 mmol scale in 0.1 M concentration.

b

Isolated yield.