Table 2.
Characteristics of patient and treatment groups n (%)
| Chemo only (n = 153 ) | Chemoradiation (n = 61) | Surgery (n = 114 ) | P value | |
| Age group (yr) | < 0.0001 | |||
| 18-49 | 29 (19.0) | 10 (16.4) | 29 (25.4) | |
| 50-64 | 62 (40.5) | 20 (32.8) | 44 (38.6) | |
| 65-79 | 55 (35.9) | 31 (50.8) | 39 (34.2) | |
| ≥ 80 | 7 (4.6) | 0 (0.0) | 2 (1.8) | |
| Sex | 0.000 | |||
| Men | 57 (37.3) | 36 (59.0) | 69 (60.5) | |
| Women | 96 (62.7) | 25 (41.0) | 45 (39.5) | |
| Race | 0.002 | |||
| Non-hispanic white | 74 (48.4) | 26 (42.6) | 53 (46.5) | |
| Black | 9 (5.9) | 7 (11.5) | 4 (3.5) | |
| Hispanic white | 37 (24.2) | 8 (13.1) | 29 (25.4) | |
| Other | 33 (21.6) | 20 (32.8) | 28 (24.6) | |
| Socioeconomic status | 0.046 | |||
| Highest | 38 (24.8) | 18 (29.5) | 33 (28.9) | |
| Middle | 96 (62.7) | 35 (57.4) | 65 (57.0) | |
| Lowest | 19 (12.4) | 8 (13.1) | 16 (14.0) | |
| Tumor | 0.000 | |||
| Liver | 21 (13.7) | 3 (4.9) | 22 (19.3) | |
| Location | ||||
| Bile duct | 132 (86.3) | 58 (95.1) | 92 (80.7) | |
| Grade | 0.685 | |||
| Well differentiated | 12 (19.4) | 4 (17.4) | 19 (21.1) | |
| Moderately differentiated | 20 (32.3) | 5 (21.7) | 33 (36.7) | |
| Poorly differentiated | 30 (48.4) | 14 (60.9) | 38 (42.2) | |
| Tumor size (cm) | 0.060 | |||
| ≤ 5 | 10 (27.8) | 7 (58.3) | 34 (50.0) | |
| > 5 | 26 (72.2) | 5 (41.7) | 34 (50.0) | |
| Summary | 0.000 | |||
| Local | 17 (15.3) | 9 (21.4) | 35 (36.1) | |
| Stage | ||||
| Regional | 29 (26.1) | 16 (38.1) | 36 (37.1) | |
| T stage | 0.001 | |||
| T1 | 23 (24.5) | 8 (19.5) | 37 (37.4) | |
| T2 | 2 (2.1) | 3 (7.3) | 14 (14.1) | |
| T3 | 19 (20.2) | 10 (24.4) | 18 (18.2) | |
| T4 | 50 (53.2) | 20 (48.8) | 30 (30.3) | |
| N stage | 0.211 | |||
| N0 | 53 (72.6) | 22 (68.8) | 71 (79.8) | |
| N1 | 20 (27.4) | 10 (31.3) | 18 (20.2) | |
| M stage | < 0.0001 | |||
| M0 | 60 (46.9) | 32 (68.1) | 96 (87.3) | |
| M1 | 68 (53.1) | 15 (31.9) | 14 (12.7) | |
| AJCC7 stage | < 0.0001 | |||
| I | 13 (14.4) | 2 (6.3) | 34 (36.6) | |
| II | 1 (1.1) | 2 (6.3) | 9 (9.7) | |
| III | 18 (11.8) | 7 (11.5) | 23 (20.2) | |
| IV | 58 (64.4) | 21 (65.6) | 27 (29.1) | |
| Chemotherapy | 153 (100.0) | 61 (100.0) | 41 (36.0) | < 0.0001 |
| Radiation | 0 (0.0) | 61 (100.0) | 25 (21.9) | < 0.0001 |
In general, characteristics that were different between the surgical patients and the non-surgical patients were age, gender, tumor location, and stage. Patients in the surgery cohort were more often male, white, and young. chemo: Chemotherapy; AJCC: American Joint Committee on Cancer.