TABLE 1.
Tissues | ROH |
Retinyl ester |
Retinol Eqv. |
||||||
---|---|---|---|---|---|---|---|---|---|
Wild-type | Stra6-null | p value | Wild-type | Stra6-null | p value | Wild-type | Stra6-null | p value | |
μg/g tissue | μg/g tissue | ||||||||
Plasma (μg/dl) | 29.1 ± 12.4 | 26.4 ± 8.8 | 0.63 | ND | ND | 29.1 ± 12.4 | 26.4 ± 8.8 | 0.63 | |
Adipose | 0.58 ± 0.32 | 0.49 ± 0.22 | 0.53 | 1.03 ± 0.82 | 1.49 ± 0.9 | 0.30 | 0.69 ± 0.42 | 1.29 ± 0.63 | 0.65 |
Brain | 0.29 ± 0.07 | 0.35 ± 0.14 | 0.49 | 0.14 ± 0.24 | ND | 0.34 ± 0.59 | 0.36 ± 0.14 | 0.96 | |
Heart | 1.51 ± 1.36 | 1.72 ± 1.79 | 0.80 | 1.43 ± 1.27 | 1.00 ± 0.85 | 0.61 | 1.98 ± 2.14 | 1.83 ± 1.8 | 0.89 |
Kidney | 0.35 ± 0.08 | 0.36 ± 0.07 | 0.78 | 0.30 ± 0.24 | 0.13 ± 0.05 | 0.09 | 0.25 ± 0.19 | 0.21 ± 0.19 | 0.69 |
Liver | 6.43 ± 2.87 | 7.55 ± 4.47 | 0.60 | 176.17 ± 50.89 | 173.39 ± 49.70 | 0.92 | 99.80 ± 29.42 | 99.44 ± 26.73 | 0.98 |
Lungs | 1.98 ± 0.48 | 2.83 ± 1.91 | 0.25 | 120.24 ± 36.13 | 145.40 ± 58.47 | 0.35 | 65.71 ± 19.43 | 79.88 ± 32.54 | 0.34 |
Muscle | 0.21 ± 0.04 | 0.25 ± 0.19 | 0.60 | 0.80 ± 0.73 | 0.56 ± 0.23 | 0.50 | 0.31 ± 0.28 | 0.50 ± 0.48 | 0.35 |
Pancreas | 0.41 ± 0.12 | 0.58 ± 0.32 | 0.18 | ND | ND | 0.41 ± 0.12 | 0.58 ± 0.32 | 0.18 | |
Spleen | 0.39 ± 0.32 | 0.53 ± 0.45 | 0.50 | 0.65 ± 0.09 | 0.52 ± 0.24 | 0.43 | 0.43 ± 0.34 | 0.53 ± 0.44 | 0.63 |
Testis | 0.11 ± 0.07 | 0.13 ± 0.13 | 0.75 | 0.49 ± 0.34 | 0.48 ± 0.18 | 0.96 | 0.49 ± 0.45 | 0.28 ± 0.24 | 0.28 |