FIGURE 4.

Comparison of the sequence of the region surrounding the dimethylated arginine residue in the bovine 49-kDa subunit of complex I with orthologous sequences. Residues 75–95 of the bovine protein were aligned with ClustalW with related sequences from the 49-kDa subunits of the human, P. pastoris, and P. denitrificans enzymes and subunit NuoCD from the E. coli enzyme. The symbols * and : denote identical and conserved residues, respectively. The shaded arginine residues are modified by symmetrical dimethylation.