Figure 4.

The effect of X-ray irradiation on lung cancer cells with hypermethylated or unmethylated Axin gene. A shows the effect of X-ray irradiation on cell apoptosis in lung cancer cells by flow cytometric analysis. The histogram in B summarizes the statistical data from A. The rate of colony formation in H157 and LTE cells with or without X-ray irradiation are shown in C, and the histogram in D summarizes the statistical data from C. The invasive cell numbers in H157 and LTE cells (treated or untreated with X-ray) are presented in E, F is the histogram of E. The cell apoptosis rate, colony formation rate and cell invasiveness are markedly changed when H157 and LTE cell lines are treated with X-ray irradiation, with a more prominent inhibitory effect seen in the H157 cell line than in the LTE cell line (A-F). * P<0.05, comparison between the two cell lines.