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Expression of NLRP3 and ASC in brain homogenates. Expression of NLRP3/GAPDH (A) and ASC/GAPDH (B) in brain homogenates of WT, Asc−/− and Nlrp3−/− mice 6 hours and 30 hours after induction of S. pneumoniae meningitis compared to mice inoculated with saline. Three mice per group were analysed in the sham infected mice and the 6 hour timepoint; 4 mice were analyzed at the 30 hour timepoint. Data are given as means +/− SD.
