Table 1.
Characteristics of the two groups of participants
| Variables | CAP (n=236) | Healthy (n=105) | p-value | Adjusted p-values* |
|---|---|---|---|---|
| |
Mean (95% CI) |
|
|
|
|
Age in years |
4.7 (0.7-14) |
6 (1.2-15.1) |
<0.001 |
- |
| Range (min-max) |
0.24-15.3 |
0.20-16.3 |
|
|
|
CRP level mg/L |
102 (9.6-315.2) |
NA |
- |
- |
|
WBC count, cells *109/L |
15.4 (4.5-35.6) |
NA |
- |
- |
|
PCT |
7.8 (0.06-57.8) |
NA |
- |
- |
| |
n (%) |
|
|
|
|
Male |
116/229 (51) |
71/105 (68) |
0.004 |
- |
|
Fully vaccinated with PCV-7 |
57/216 (26) |
13/97 (13) |
0.004 |
- |
|
Day care/school attendance |
167/226 (74) |
82/102 (80) |
0.20 |
0.94 |
|
Number of siblings >1 |
152/223 (68) |
76/103 (74) |
0.30 |
0.56 |
|
Positive tobacco exposure |
64/219 (29) |
39/100 (39) |
0.08 |
0.13 |
| Nasopharyngeal SP_ PCR positive | 127 (54) | 34 (32) | <0.0001 | 0.003 |
CAP indicates Community-acquired pneumonia; SP, Streptococcus pneumoniae; n, number; CRP, C reactive protein; WBC, white blood cell; PCT, Procalcitonin; NA, not applicable.
* Chi-Square test adjusted by age, gender and PCV7 vaccination status (fully, partially or not).