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. 2013 Aug 6;8:116. doi: 10.1186/1750-1172-8-116

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Copyright © 2013 Weidemann et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Kidney biopsy. A) PAS staining. Histology of the kidney with characteristic changes of advanced Fabry nephropathy. Please note glomerular segmental sclerosis (A), adhesion and Bowman capsule reduplication (B), tubular atrophy and tubular cell related fibrosis (thickened basement membranes) (C) and arteriolar hyalinosis (D). Original magnification 63×. Courtesy of Prof. Justus Müller, Department of Pathology, University Hospital of Würzburg, Würzburg, Germany. B) Sirius red staining of collagen fibers illustrates peri-glomerular fibrosis (E) and interstitial fibrosis (F). Original magnification × 20.