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In vitro cytotoxicity of acridone 1, 4, 7 and 8
| |
IC50 expressed in μM |
|||
|---|---|---|---|---|
| Compounds | WRL-68 | CaCO2 | MCF-7 | PC-3 |
|
1 |
86 |
>300 |
229 |
272 |
|
4 |
>300 |
>300 |
>300 |
>300 |
|
7 |
>300 |
>300 |
>300 |
>300 |
|
8 |
>300 |
>300 |
205 |
>300 |
| Doxorubicin | 1.4 | 6.0 | 3.6 | 8.6 |
WRL-68 = Liver cancer cell lines, CaCO2 = colon cancer, MCF-7 = breast cancer, PC-3 = prostate cancer. Doxorubicin Sigma D-1515 is the standard used.
