Table 2.
List of the top GO terms in the most significant DAVID functional clusters for each muscle network module
| Module | Top term | No. of genes in ME | % count1 | Top term P-value |
|---|---|---|---|---|
| blue |
GO:0044451 ~ nucleoplasm part |
524 |
8.97 |
1.32E-11 |
| light-green |
GO:0044429 ~ mitochondrial part |
97 |
59.79 |
3.24E-54 |
| dark-orange |
GO:0006414 ~ translational elongation |
24 |
41.67 |
1.37E-14 |
| grey60 |
GO:0030163 ~ protein catabolic process |
105 |
12.38 |
3.10E-04 |
| magenta |
GO:0046907 ~ intracellular transport |
208 |
10.58 |
3.43E-05 |
| red |
GO:0005761 ~ mitochondrial ribosome |
315 |
5.08 |
4.41E-16 |
| black |
GO:0005739 ~ mitochondrion |
436 |
27.06 |
4.88E-46 |
| salmon |
GO:0006414 ~ translational elongation |
137 |
45.99 |
4.93E-107 |
| green |
GO:0032446 ~ protein modification by small protein conjugation |
246 |
4.07 |
7.90E-05 |
| dark-grey |
GO:0030036 ~ actin cytoskeleton organisation |
37 |
16.22 |
8.94E-05 |
| tan |
GO:0031012 ~ extracellular matrix |
154 |
31.17 |
7.96E-39 |
| midnightblue |
GO:0042060 ~ wound healing |
122 |
7.38 |
5.38E-05 |
| pink |
GO:0000323 ~ lytic vacuole |
265 |
10.57 |
2.78E-16 |
| dark-turquoise |
GO:0006006 ~ glucose metabolic process |
31 |
16.13 |
3.00E-04 |
| purple |
GO:0006986 ~ response to unfolded protein |
143 |
6.38 |
8.28E-08 |
| light-yellow |
GO:0006954 ~ inflammatory response |
85 |
14.12 |
7.94E-07 |
| orange |
GO:0009611 ~ response to wounding |
26 |
23.08 |
1.37E-03 |
| brown |
GO:0031981 ~ nuclear lumen |
1436 |
15.48 |
2.72E-27 |
| dark-red |
GO:0031981 ~ nuclear lumen |
183 |
21.86 |
8.14E-10 |
| cyan |
GO:0044265 ~ cellular macromolecule catabolic process |
182 |
13.19 |
1.61E-06 |
| dark-green |
GO:0019941 ~ modification-dependent protein catabolic process |
38 |
13.16 |
2.93E-02 |
| grey | GO:0008219 ~ cell death | 3616 | 23.84 | 7.09E-17 |
1(number of genes in term/number of genes in ME) × 100).