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. 2013 Jul 5;12:98. doi: 10.1186/1475-2840-12-98

Table 4.

Independent correlates of any CVD event(s)

Variables
Any CVD event
  OR 95%CI P
Age, x year
1.018
1.011-1.024
<0.0001
Diabetes duration, x year
1.019
1.013-1.025
<0.0001
Gender, male
1.746
1.550-1.967
<0.0001
BMI, x unit
-
-
-
Smoking
 
 
<0.0001
  No
1.0
 
 
  Former
1.413
1.254-1.591
<0.0001
  Current
1.156
0.986-1.354
0.074
Triglycerides, x 0.0113 mmol/l
0.999
0.999-1.000
0.040
HDL cholesterol, x0.259mmol/l
0.983
0.978-0.987
<0.0001
Dyslipidemia
1.713
1.470-1.997
<0.0001
Hypertension
2.054
1.699-2.484
<0.0001
Diabetes treatment, n (%)
 
 
<0.0001
  Diet
1.0
 
 
  OHA
1.266
1.038-1.544
0.020
  Insulin + OHA
1.228
0.942-1.601
0.128
  Insulin
2.051
1.623-2.593
<0.0001
Albuminuria
 
 
0.052
  Normoalbuminuria
1.0
 
 
  Microalbuminuria
1.167
1.030-1.323
0.015
  Macroalbuminuria
1.069
0.845-1.351
0.580
eGFR (MDRD)
 
 
<0.0001
  ≥90 ml/min/1.73 m2
1.0
 
 
  6089 ml/min/1.73 m2
1.116
0.975-1.278
0.112
  3059 ml/min/1.73 m2
1.820
1.531-2.162
<0.0001
  <30 ml/min/1.73 m2
2.278
1.541-3.367
<0.0001
Retinopathy
 
 
<0.0001
  No retinopathy
1.0
 
 
  Non advanced retinopathy
1.295
1.122-1.495
0.0001
  Advanced retinopathy
1.298
1.084-1.554
0.005
MODEL 1
 
 
 
  HbA1c-MEAN, 1% increment
1.062
1.011-1.114
0.016
MODEL 2
 
 
 
  HbA1c-MEAN, 1% increment
1.062
1.011-1.114
0.016
  HbA1c-SD, 1% increment
-
-
-
MODEL 3
 
 
 
HbA1c-MEAN
 
 
0.001
  quartile 1
1.0
 
 
  quartile 2
0.923
0.787-1.082
0.322
  quartile 3
1.248
1.066-1.462
0.006
  quartile 4
1.096
0.928-1.295
0.281
HbA1c-SD quartiles

Logistic regression analysis with backward variables selection of independent correlates of any CVD event versus no CVD event. ORs of variables except HbA1c-MEAN, HbA1c-SD, and their quartiles were determined by multivariate logistic analysis from MODEL 1. The results did not change significantly in MODEL 2 and MODEL 3.