Table I.

Mortality risk according to TC derived from the Cox regression analysis shown as the hazard ratio (HR), p-value and the 95% confidence interval (95% CI).

		HR	p-value	95% CI		HR	p-value	95% CI
Parameter	n	Males			n	Females
50–60 years		N = 25 840; C = 1572				N = 25 743; C = 866
TC < 5 mmol/L1	5450				3957
TC 5–5.99 mmol/L	9100	0.73	< 0.001	0.64–0.82	8,637	0.68	< 0.001	0.56–0.82
TC 6–7.99 mmol/L	10 278	0.68	< 0.001	0.59–0.77	11 682	0.71	< 0.001	0.59–0.86
TC ≥ 8 mmol/L	1012	1.07	0.601	0.83–1.37	1467	1.00	0.977	0.74–1.36
Statin	7373	0.62	< 0.001	0.55–0.70	6835	0.63	< 0.001	0.53– 0.74
School 12–15 years		0.63	< 0.001	0.57–0.69		0.66	< 0.001	0.58–0.76
School ≥ 15 years		0.44	< 0.001	0.30–0.63		0.60	0.038	0.37–0.97
60–70 years2		N = 19 843; C = 2379				N = 20 367; C = 1641
TC < 5 mmol/L1	4047				2170
TC 5–5.99 mmol/L	7161	0.68	< 0.001	0.61–0.77	5795	0.57	< 0.001	0.48–0.67
TC 6–7.99 mmol/L	8001	0.67	< 0.001	0.59–0.75	10 809	0.59	< 0.001	0.50–0.68
TC ≥ 8 mmol/L	634	1.02	0.914	0.68–1.53	1593	1.02	0.866	0.77–1.37
Statin	6971	0.67	< 0.001	0.55–0.83	7214	0.66	0.029	0.46–0.96
School 12–15 years		0.81	< 0.001	0.74–0.88		0.72	< 0.001	0.65–0.80
School ≥ 15 years		0.53	< 0.001	0.40–0.71		0.81	0.204	0.59–1.12
> 70 years		N = 11 685; C = 3503				N = 14 682; C = 3039
TC < 5mmol/L1	3,183				1,789
TC 5–5.99 mmol/L	4,308	0.70	< 0.001	0.65–0.76	4,207	0.65	< 0.001	0.58–0.72
TC 6–7.99 mmol/L	3,956	0.62	< 0.001	0.57–0.68	7,581	0.52	< 0.001	0.47–0.57
TC ≥ 8 mmol/L	238	0.67	0.001	0.52–0.86	1,105	0.59	< 0.001	0.50–0.69
Statin	3,675	0.64	< 0.001	0.59–0.69	4,613	0.60	< 0.001	0.55–0.65
School 12–15 years		0.84	< 0.001	0.78–0.90		0.84	< 0.001	0.78–0.92
School ≥ 15 years		0.79	0.022	0.65–0.97		0.82	0.179	0.61–1.10

Notes: N = numbers in the specific age and sex group, C = cases (died in the study period more than one year after inclusion), and n = numbers in each TC group or numbers receiving statin after inclusion. ¹The TC group < 5 mmol/L is the reference group and only the numbers in this group are therefore reported. ²The results shown are adjusted for the found interaction between TC and statin use in both males and females aged 60–70 years.